Home  .  RNAi  .  RNAi: siRNA generation kits  .  Recombinant Dicer Enzyme Kits
Home  .  RNAi  .  Dicer Enzyme Kits  .  Recombinant Dicer Enzyme Kits

RNAi: siRNA generation kits
Recombinant Dicer Enzyme Kits
  • No guesswork – A mixture of siRNAs has a better chance of success than a single siRNA design.
  • No wasted time and money due to failed siRNA designs
  • More regions of the genes can be screened for silencing

The Recombinant Human Dicer Enzyme Kit uses an ultra-active form of human recombinant dicer enzyme that can cleave more than 95% of dsRNA template into 22 bp siRNAs within 12 hours under optimized reaction conditions (Figure 1). This provides sufficient siRNAs in every single species to achieve effective gene silencing(1). siRNAs are 21- to 23-nucleotide RNA molecules that can cause targeted gene silencing in mammalian cells through a process known as RNA interference (2,3,4). In nature, siRNAs are generated by ribonuclease III cleavage of longer double stranded RNAs (dsRNAs). When dsRNAs are transfected directly into mammalian cells, they activate the interferon system and provoke non-specific gene suppression and cytotoxic response (2). siRNAs have proven to be effective at specifically silencing gene expression without causing any interferon response.

Storage
The Dicer Enzyme Kit is shipped on dry ice. The recombinant human dicer enzyme should be stored at –20°C upon receipt. If stored properly, all reagents are stable for 6 months.

References:
1. Myers, J.W. et al. (2003) Nature Biotechnology 21: 324-328.
2. Elbashir, S.M. et al. (2001) Nature 411: 494-498.
3. Caplen, N.J. et al. (2001) Proc Natl Acad Sci USA 98: 9742-9747.
4. Sharp, P.A. (2001) Genes and Development 15: 485-490.

Recombinant Dicer Enzyme Kits


  • Recombinant Dicer Enzyme - 50 units, T510002 - $326
  • Recombinant Dicer Enzyme - 4 x 50 units, T510008 - $1,064

  • http://www.genlantis.comdicer-enzyme.html
    $326.00
    Recombinant Dicer Enzyme Kits
    Click to Enlarge

    Recombinant Dicer Enzyme Kits

    Item #:dicer-enzymeIn stockUsually ships the same business day
    Price based on size, select below
    Recombinant Dicer Enzyme Kits:
    Download User Manual
    Quantity
    | More


    Description
    • No guesswork – A mixture of siRNAs has a better chance of success than a single siRNA design.
    • No wasted time and money due to failed siRNA designs
    • More regions of the genes can be screened for silencing

    The Recombinant Human Dicer Enzyme Kit uses an ultra-active form of human recombinant dicer enzyme that can cleave more than 95% of dsRNA template into 22 bp siRNAs within 12 hours under optimized reaction conditions (Figure 1). This provides sufficient siRNAs in every single species to achieve effective gene silencing(1). siRNAs are 21- to 23-nucleotide RNA molecules that can cause targeted gene silencing in mammalian cells through a process known as RNA interference (2,3,4). In nature, siRNAs are generated by ribonuclease III cleavage of longer double stranded RNAs (dsRNAs). When dsRNAs are transfected directly into mammalian cells, they activate the interferon system and provoke non-specific gene suppression and cytotoxic response (2). siRNAs have proven to be effective at specifically silencing gene expression without causing any interferon response.

    Storage
    The Dicer Enzyme Kit is shipped on dry ice. The recombinant human dicer enzyme should be stored at –20°C upon receipt. If stored properly, all reagents are stable for 6 months.

    References:
    1. Myers, J.W. et al. (2003) Nature Biotechnology 21: 324-328.
    2. Elbashir, S.M. et al. (2001) Nature 411: 494-498.
    3. Caplen, N.J. et al. (2001) Proc Natl Acad Sci USA 98: 9742-9747.
    4. Sharp, P.A. (2001) Genes and Development 15: 485-490.

    Recombinant Dicer Enzyme Kits


  • Recombinant Dicer Enzyme - 50 units, T510002 - $326
  • Recombinant Dicer Enzyme - 4 x 50 units, T510008 - $1,064


  • Stay Updated
    Join our mailing list today to receive all the latest updates and information!
    Corporate Headquarters
    • Genlantis, Inc.
    • 11011 Torreyana Rd
    • San Diego, CA 92121
    • 1-888-428-0558
    Shop With Confidence
    This shopping cart employs the highest industry strength security: 256 bit SSL E-commerce by Yahoo! We accept Visa, Master Card, American Express, Discover, PayPal
    © 2013 Genlantis Inc. All rights reserved. Yahoo! Store by Solid Cactus